Skip to main content

Dr. Daniel Nasrallah

Assistant Professor

Department:
Chemistry
Location:
565A Trexler Hall
Phone:
(540)375-5158

Degrees

  • B.S. in Chemistry with a Concentration in Research, University of North Carolina at Greensboro
  • Ph.D. in Chemistry, University of Michigan
  • Post-doc, University of California, Los Angeles

Research & Teaching Interests

  • My research interests focus on the education and development of undergraduate researchers in a scientifically rigorous and intentionally inclusive environment. Projects target investigations of transition metal-free methods to make key bonds to carbon.

Publications

  • Ippoliti, F. M.; Wonilowicz, L. G.; Adamson, N. J.; Darzi, E. R.; Donaldson, J. S.; Nasrallah, D. J.; Mehta M. M.; Kelleghan, A. V.; Garg, N. K. Total Synthesis of Lissodendoric Acid A. Angewandte Chemie International Edition 2024, 63, e202406676.
  • Bulger, A.;† Nasrallah, D. J.;† Tena Meza, A.;† Garg, N. K. Enantioselective Nickel-Catalyzed Mizoroki–Heck Cyclizations of Amide Electrophiles. Chemical Science 2024, 15, 2593–2600.
  • Nasrallah, D. J.; Garg, N. K. Studies Pertaining to the Emerging Cannabinoid Hexahydrocannabinol (HHC). ACS Chemical Biology 2023, 18, 2023–2029.
  • Zehnder, T. E.; Nasrallah, D. J.; Stanley, J. L.; Kiernicki, J. J.; Szymczak, N. K.; Schindler, C. S. Development of an In Situ Protocol for the Intramolecular Olefination of Oximes. Organometallics 2023, 42, 479–485.
  • McAtee, C. C.; Nasrallah, D. J.; Ryu, H.; Gatazka, M. R.; McAtee, R. C.; Baik, M.-H.; Schindler, C. S. Catalytic, Interrupted Carbonyl-Olefin Metathesis for the Formation of Functionalized Cyclopentadienes. ACS Catalysis 2023, 13, 3036–3043.
  • Ippoliti, F. M.;† Adamson, N. J.;† Wonilowicz, L. G.; Nasrallah, D. J.; Darzi, E. R.; Donaldson, J. S.; Garg, N. K. Total Synthesis of Lissodendoric Acid A via Stereospecific Trapping of a Strained Cyclic Allene. Science 2023, 379, 261–265.
  • Nasrallah, D. J.;† Zehnder, T. E.;† Ludwig, J. R.; Steigerwald, D. C.; Kiernicki, J. J.; Szymczak, N. K.; Schindler, C. S. Hydrazone and Oxime Olefination via Ruthenium Alkylidenes. Angewandte Chemie International Edition 2022, 61, e202112101.
  • Davis, A. J.;† Watson, R. B.;† Nasrallah D. J.; Gomez-Lopez, J. L.; Schindler, C. S. Superelectrophilic Aluminum(III)-Ion Pairs Promote a Distinct Reaction Path for Carbonyl-Olefin Ring Closing Metathesis. Nature Catalysis 2020, 3, 787–796.
  • Riehl, P. R.; Nasrallah, D. J.; Schindler, C. S. Catalytic, Transannular Carbonyl-Olefin Metathesis Reactions. Chemical Science 2019, 10, 10267–10274.
  • Ludwig, J. R.; Watson, R. B.;† Nasrallah, D. J.;† Gianino, J. B.; Zimmerman, P. M.; Wiscons, R. A.; Schindler, C. S. Interrupted Carbonyl-Olefin Metathesis via Oxygen Atom Transfer. Science 2018, 361, 1363–1369.
  • Fakhouri, L; Cook, C.; Al-Huniti, M.; Console-Bram, L.; Hurst, D.; Spano, M.; Nasrallah, D.; Caron, M.; Barak, L.; Reggio, P.; Abood, M.; Croatt, M. Design, Synthesis and Biological Evaluation of GPR55 Agonists. Bioorganic & Medicinal Chemistry 2017, 25, 4355–4367.
  • Hyatt, I. F. D.; Nasrallah, D. J.; Maxwell, M. A.; Hairston, A. C. F.; Abdalhameed, M. M.; Croatt M. P. Formation and in situ Reactions of Hypervalent Iodonium Alkynyl Triflates to form Cyanocarbenes. Chemical Communications 2015, 51, 5287–5289.
  • Smith, C. L.; Hirschhäuser, C.; Malcolm, G. K.; Nasrallah, D. J.; Gallagher T. Synthesis of Mono- and Diaza-‘Pyridones’ via Stille Coupling of Alkoxystannanes. Synlett 2014, 13,1904–1908.
  • Nasrallah, D. J.; Croatt, M. P. Rhodium(I)-Catalyzed [2+2+2+2] Cycloaddition of a Diyne to form a Cyclooctatetraene. European Journal of Organic Chemistry 2014, 18, 3767.
  • Hyatt, I. F. D.; Nasrallah, D. J.; Croatt, M. P. Synthesis of Hypervalent Iodonium Alkynyl Triflates for the Application of Generating Cyanocarbenes. Journal of Visualized Experiments 2013, 79, e50886, DOI:10.3791/50886.

Available as a Media resource for the following topics

  • Organic Chemistry
  • Synthetic cannabinoids and their syntheses

Willing to speak to professional, social or civic groups on

  • Organic Chemistry
  • Synthetic cannabinoids and their syntheses